IWR - Simulation and Optimization

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    [Simon Lenz]
Open Positions
Simon M. Lenz

Please note:
In January 2015, I started to work at Rating Service Unit GmbH in Munich

Simon M. Lenz



Dr. rer. nat. Simon M. Lenz
Interdisciplinary Center for Scientific Computing (IWR)
Im Neuenheimer Feld 368
D-69120 Heidelberg (Germany)

Room: 412


+49 6221 54 8897



Research Interests


Parameter Estimation
Optimum Experimental Design

Simulation and Sensitivity Computation:

Delay Differential Equations
Differential Equations with Discontinuities and Nondifferentiabilities
Differential Algebraic Equations
Ordinary Differential Equations


Systems Biology
Space Flight
Chemical Engineering

Posters and Talks at Conferences and Workshops

"Delayed Feedback in the Livescore of a Television Singing Competition (Poster),
International Conference on Delayed Complex Systems,
June 2012, Palma de Mallorca, Spain

"Delay Effects in the Livescore of 'Unser Star für Baku'" (Talk),
Opening Ceremony of the Heidelberg Chapter of SIAM,
March 2012, Heidelberg, Germany

"Numerical Derivative Computation by Adjoint Methods for Delay Differential Equations" (Talk),
International Congress on Industrial and Applied Mathematics (ICIAM),
July 2011, Vancouver, BC, Canada

"Derivative Computation and Parameter Estimation for DDE Models in Biology" (Poster),
Delay Differential Equations in Applications: Common Themes and Methods,
July 2011, Vancouver, BC, Canada

"Parameter Estimation with Derivative Based Methods for Delay Differential Equations in Systems Biology" (Talk),
International Workshop on Differential and Integral Equations with Applications in Biology and Medicine,
September 2010, Karlovassi, Samos, Greece

"Efficient Derivative Computation for Delay Differential Equations" (Talk),
International Workshop on State Dependent Delay Equations,
October 2009, Dresden, Germany

"Initial Satellite Orbit Determination with a Direct Multiple Shooting Method" (Talk),
4th International Conference on High Performance Scientific Computing,
March 2009, Hanoi, Vietnam

Publications / Theses

"Impulsive Hybrid Discrete-Continuous Delay Differential Equations"
PhD Thesis, University of Heidelberg, 2014

"Numerical Computation of Derivatives in Systems of Delay Differential Equations"
S.M. Lenz, J.P. Schlöder, and H.G. Bock
Mathematics and Computers in Simulation, Volume 96, pp 124-156, February 2014

"Replication Vesicles are Load- and Choke-Points in the Hepatitis C Virus Lifecycle",
M. Binder, N. Sulaimanov, D. Clausznitzer, M. Schulze, C.M. Hüber, S.M. Lenz, J.P. Schlöder, M. Trippler, R. Bartenschlager, V. Lohmann, L. Kaderali
PLoS Pathogens, Volume 9, No. 8, August 2013

"Multiple Shooting Method for Initial Satellite Orbit Determination",
S.M. Lenz, H.G. Bock, J.P. Schlöder, E.A. Kostina, G. Gienger, G. Ziegler
AIAA Journal on Guidance, Control and Dynamics, Volume 33, No. 5, pp 1334-1346, September 2010.

"Solution of Parameter Estimation Problems with the
Direct Multiple Shooting Method in Discontinuous Models",
Diploma Thesis, University of Heidelberg, 2008


Numerische Mathematik 2 - Optimierung bei gewöhnlichen Differentialgleichungen
Summer Semester 2014, Heidelberg

Compact Course "Parameter Estimation and Optimum Experimental Design"
April 2012, Heidelberg

Compact Course "State-Space System Identification"
July 2010, Heidelberg
(Organizer and Lecturer)

Compact Course "Optimization with Differential Equations"
July 2009, Heidelberg

Student Mentoring

Lukas Schork, "Numerical Treatment of Discontinuous Initial Value Problems in Satellite Orbit Simulations"
Bachelor Thesis, February 2014

Manuela Kuhn, "Solution of Nonlinear Optimization Problems constrained by Delay Differential Equations with an Application to a Gene Regulatory Network"
Diploma Thesis, December 2013

Jamin Hass, "Automatische Regularisierung beim Gauß-Newton-Verfahren für Parameterschätzprobleme über eine Schätzung der Imkompatibilitätskonstanten Kappa"
Diploma Thesis, January 2012

Shashank Jaiswal, "Local Minima in Parameter Estimation Problems for a Predator-Prey Model"
Software Practical, January 2012

Natalie Grassmuck, "Detection of Discontinuities of Parameters with a Multiple Shooting Method for Adaptivity in Parameter Estimation"
Diploma Thesis, April 2011

Manuela Ernst, Lösung von Anfangswertproblemen bei verzögerten Differentialgleichungen mit SolvIND
Bachelor Thesis, June 2011

Philipp Weidmann, "Moving Horizon Estimation and Satellite Orbit Determination"
Diploma Thesis, January 2011

Jamin Hass, "Satellite Orbit Determination with Nonsingular Kepler Elements"
Software Practical, March 2010

Jerko Horvat, "Visualisierung von Satellitenbahnen"
Software Practical, November 2008

Short CV

Oct. 2002 - Sep. 2004:		Studying Physics at Dortmund University
Sep. 2004: Vordiplom in Physics
Oct. 2004 - Mar. 2008: Studying Physics at Heidelberg University
Mar. 2008: Diplom in Physics
Apr. 2008 - Jun. 2014: PhD Project in Mathematics at Heidelberg University "Impulsive Hybrid Discrete-Continuous Delay Differential Equations" May 2008 - Jun. 2014: Member of the Heidelberg Graduate School of Mathematical and Computational Methods for the Sciences (HGS MathComp) May 2012 - Nov. 2013: Fellows' Representative of the HGS MathComp Jul. 2014 - Dec. 2014: Postdoctoral Researcher at Heidelberg University

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Last Modified By: Simon M. Lenz
Last Update:2014-12-17
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